The 2005 Caprini Risk Assessment Model sums ~40 weighted factors (1, 2, 3, or 5 points each) into a single integer, then maps that integer onto one of four VTE-prophylaxis tiers from mechanical-only (score 0) to LMWH for 30 days (score ≥9). This guide covers the management tiers, the thrombophilia and 5-point orthopedic exposures that dominate the score, and the audit gaps that show up most often in pre-operative and same-day surgery clinics.

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